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H&E staining and Ki67 assay showed that GOx/CuSAE significantly inhibited the growth of tumor cells in vivo, while CuSAE demonstrated a moderate inhibitory effect (Fig

Patients with wasting diseases (most famously HIV/AIDS) Patients with lung cancer and other pulmonary diseases Patients with major injuries, sepsis, and trauma Patients with gut diseases like Inflammatory Bowel Disease (Crohns Disease and ulcerative colitis) Patients with Chronic Fatigue Syndrome Overtrained athletes People with alcoholism or fatty liver disease People with diabetes and lower glucose tolerance In many of these cases, raising glutathione levels has shown some therapeutic benefits

Glutathione is generally well-tolerated, but people with asthma, sulfur sensitivity, or certain medical conditions should consult a doctor

Int J Mol Sci 21: 5895, 2020

However, in PEM patients, underlying pathological conditions, such as persistent viral infections in PCC (105), prevent the effective resolution of mitochondrial stress, thereby triggering the potential onset of a pathological cycle