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doi: 10.1038/sj.embor.7400731 241 OeckinghausA.GhoshS

The purpose of this state-of-the-art critical narrative review is to integrate disparate mechanistic, pre-clinical, and clinical data into a coherent conceptual model of phytochemical action in depression rather than to catalogue every published study

et al., 2025), these indicators are still in the exploratory stage, with no standardized detection protocols established or their clinical significance validated in large-scale clinical samples

hypoxia inducible factor (HIF) proteasomal degradation and 3

Clinical trials indicate bethanechol is no more effective than placebo, and its use is associated with significant dose-dependent unpleasant side effects including blurred vision, bradycardia, bronchospasm, and GI upset (Barrett 1981
