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Variants in CD44, CYP3A5, UGT1A9, UGT1A1, UGT2B15 impact risk
Thus, cancer treatment strategies have focused on pharmacological inhibition of these transporters
Chen, Y., Siewers, V
For this reason we believe the most effective plasmid design should place Gpx closest to the promoter, where it has the highest probability of being fully transcribed by RNA polymerase, and GR furthest from the promoter, since high concentrations of GR appear to be less critical given its efficacy
doi: 10.3390/biomedicines10071462
