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Affecting over 10% of women of reproductive age, PCOS is not just a condition characterized by irregular periods and cysts on the ovaries

ROS directly or indirectly affect ASK1, MEKK1/2/3/4, and MLK3, which subsequently activate MEK3/6 (highly conserved in the p38 pathway)
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10.4103/pm.pm_595_17 [DOI] [Google Scholar] 77.Dias TR, Bernardino RL, Alves MG, Silva J, Barros A, Sousa M, et al