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[47] The importance of regulating the conversion of pyruvate into acetyl-CoA is also underscored by the fact that mammals, although able to produce glucose from pyruvate, cannot synthesize it from acetyl-CoA because of the irreversibility of the pyruvate dehydrogenase reaction and the absence of alternative pathways

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3.3.3 Enzymatic activity vs

FT-IR, mass spectrometry and NMR experiments [1D 1 H, 13 C NMR and 2D NMR (HH COSY, TOCSY, HMQC, HMBC and NOESY)] are useful in providing information for the mycochemical structural elucidation

This study provides pharmacological and genetic evidence of the blood glucose-lowering effect of AMPK activation in skeletal muscle