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Combination index (CI) was calculated using the CompuSyn software, CI 1.0 was defined as antagonism

All of these characteristics are influenced by the consistency of collagen and elastin fibers, the keratinization of the stratum corneum, the degree of hydration, and the water-binding capacity [2]

Firstly, anti-PD-1 therapy promotes lipid drop (LD) deposition in HCC, which may lead to ineffective anti-PD-1 treatment

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In some embodiments, the otic pharmaceutical formulation comprises between about 70% to about 80% by weight of the triglycerides