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As reported in an RCT with 64 HT patients, a 6-month treatment with Chuanshanlong Granule (10 g, twice daily) plus L-T4 resulted in a significant reduction in TPOAb and TGAb titers, Th17 cells and relevant cytokines compared to L-T4 alone, as well as in a significant increase in the Treg/Th17 ratio [93]
[DOI] [PubMed] [Google Scholar] 39.Itoh T, Obata H, Murakami S, Hamada K, Kangawa K, Kimura H, Nagaya N

Berberine inhibits adipocyte differentiation, proliferation and adiposity through down-regulating galectin-3

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