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Ulus Travma Acids Cerrahi Derg 30 , 229235 (2024)
doi: 10.1097/SPV.0000000000001270

TSH secretion shows a robust circadian regulation with an acrophase in the resting phase in humans and mice whereas the diurnal rhythms of THs are controversial as total and free THs show a shallow amplitude and often arrhythmicity 26,95,96,97

In this review, we provide a comprehensive and critical analysis covering the recent advances, potential challenges and future prospects regarding the design and synthesis, as well as pre- and clinical evaluation of cereblon-based PROTACs
doi: 10.1016/j.ebiom.2022.104021
