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However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007

Caution beats assumption here

[19] Cyanocobalamin vials should be stored at controlled room temperature (15 - 25 C), protected from excessive light and humidity, and kept in their original packaging to preserve potency

A high-fat/high-protein, atkins-type diet exacerbates (in Eng)

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