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Based on the assumption that -Syn dimerization on the membrane surface is crucial for the oligomerization of -Syn [317,318], they performed a molecular dynamics analysis that revealed a dimerization-responsible pharmacophore region located on residues 96102 at the C -terminal domain

5e,f), are located far from the IMiD-binding site on another face of CRBN (Extended Data Fig

The most common type, type 2 diabetes (T2DM), is characterized by dysfunctional cells and insulin resistance [113]

10.1038/sj.jid.5700701 42 EmmersonS.MukherjeeS.Melendez-MunozJ.CousinsF.EdwardsS

What is the connection between ferroptosis and other forms of cell death, and can this crosstalk further induce cell death in lung cancer