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Together, these findings identify the melatonin-NRF2-glutathione axis as a metabolic checkpoint regulating innate type 2 immunity and suggest that therapeutic targeting of redox metabolism may represent a strategy for modulating airway inflammation in allergic asthma

l-dopa) can cross the BBB and reach brain tissue via l-type amino acid transporter-1 (LAT-1), the member of solute carrier (SLC) family present at the brain endothelium and diverse brain cells [6]

This is due to a decrease in its own synthesis

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2 A single oral dose of ivermectin may be ineffective in some scabies patients due to its lack of ovocidal action, requiring a second dose to kill newly hatched mites