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And I just remember heavily trying to understand

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Histopathological analysis and immunohistochemical staining revealed decreased expression of K16, K17, and Ki67 in SFN-treated mice, indicating reduced abnormal differentiation of keratinocytes and cutaneous inflammation

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Hyaluronan is the molecule in synovial fluid that is largely responsible for the viscosity of the fluid and its breakdown products can induce an inflammatory state
