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Description
No serious long-term side effects have been reported from regular therapeutic use

these are trial protocols only, as no licensed dosing schedules or UK SmPCs exist for either agent

Food and Drug Administration: Glucophage (Metformin Hydrochloride) Tablets Label JCEM Case Reports : Metformin-Associated Vitamin B12 Deficiency: An Underrecognized Complication Clinical Diabetes : Increasing Vitamin B12 Screening Among Patients With Type 2 Diabetes on Long-Term Metformin Therapy Harvard Health Publishing: Vitamin B12 Deficiency Can Be Sneaky and Harmful Johns Hopkins Medicine: Vitamin B12 Deficiency Anemia Yale Medicine: Are You Getting Enough Vitamin B12

Factors responsible for thrombosis include, among others, vessel wall damage or slowed blood flow

Dosing Frameworks Commonly Used A typical B12 injection protocol starts with 1 mg of either form given weekly for four weeks
