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3 months

At this point, there is insufficient evidence to recommend B12 supplementation for fatigue beyond correcting a deficiency

For B12 deficiency, only take the minimum amount needed to get your levels to normal.

J Cell Physiol

"While we acknowledge your response that an abrupt shortening of the enrollment period led to challenges and mistakes, your response is inadequate because, regardless of the length of the enrollment period, you are still responsible for ensuring that subjects meet protocol-specified eligibility criteria before you enroll them into the study," said FDA
