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Astragaloside IV ameliorates myocardial injury in diabetic rats by suppressing CD36-mediated ferroptosis and reducing lipid deposition

The slices were rinsed and placed into a chamber embedded in the stage of an Olympus BX51WI microscope (Olympus) coupled to a 12-bit CCD fluorescent camera (SensiCam, PCO imaging)

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The coupled systems architecture reveals that oxidative stress and C1 metabolism interface through the ascorbate-glutathione pathway, which interfaces with the methionine biosynthesis and formaldehyde detoxification pathways of C1 metabolism

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