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In the kainate and pilocarpine rat experimental models of TLE, ROS production through NOX activity is associated with microglial activation and is responsible for neurodegeneration in these models (Patel et al., 2005

Acetylcholine is a neurotransmitter that can become overactive in PD due to the loss of dopamine (6, 51, 52)

Consequently, MSU crystals can shift local inflammation from a transient defense mechanism to ongoing tissue remodeling through the activation of inflammatory corpuscles and the programmed response of immune cells

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It is worth remembering that each person's symptoms of vitamin B12 deficiency can be different