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Description
Nuclear factor-erythroid factor 2-related factor 2 (NRF2) is a widely conserved factor which mediates the defense mechanism against oxidative stress through transcriptional regulation (195)

Knutson, C

When levels fall low enough, oxidative stress accumulates, which is associated with fatigue, compromised immune response, accelerated skin aging, and increased strain on the liver

doi: 10.1021/pr500825y

Reactive oxygen species are indispensable in ovulation
