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doi: 10.1016/S0015-0282(02)04237-1 [DOI] [PubMed] [Google Scholar] 62

Proper methylation is necessary for gene regulation, detoxification, and neurotransmitter production[197]

As a consequence of lack of physical activity and excessive energy intake, MetS has become a disease which affects more than 25 % of the world population and causes serious concerns worldwide (Grundy, 2016[21])

In another small study involving 15 patients receiving hemodialysis (where blood is pumped out of the body to an artificial kidney machine), they were found to have gastrointestinal symptoms, including constipation (likely due to restrictions in their water intake required as part of their therapy), as well as carnitine deficiency

Acetate did not detectably contribute to acetyl-CoA pools in DKO cells (Figure 5C)