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In addition, the possibility to manipulate SLC25A39 and/or to regulate the amount of GSH that enters mitochondria also offers the opportunity to study the importance of mitochondrial GSH in more detail, especially in mitochondria-rich tissues like liver or kidney

Here, we discuss both the canonical and non-canonical functions of glycolytic enzymes and evaluate their potential as therapeutic targets in AML

NADPH and ATP is mainly supplied through the fatty acid -oxidation and coupled oxidative phosphorylation, providing growth and proliferation advantages

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