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direct cell toxicity is observed at such concentrations (Fig

Integrated transcriptomic and metabolomic analyses in this study revealed that periodontitis reprograms intracellular glutathione (GSH) metabolism in BM neutrophils, facilitating their N1 polarization

It restores mitochondrial calcium homeostasis, deacetylates and activates mitochondrial SIRT3, improves the integrity of the bloodbrain barrier, and counteracts neuroinflammation and glutamate excitotoxicity (Morris et al., 2021)

Bodles AM, El-Agnaf OM, Greer B, Guthrie DJ, Irvine GB

Diagnostic utility of the glucagon stimulation test in comparison to the insulin tolerance test in patients following pituitary surgery
