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41, 42 More recently, whole duplications of the MECP2 gene have been associated with severe X-linked MR with progressive spasticity, no or poor speech acquisition and acquired microcephaly, 43 which has been recapitulated in a mouse model overexpressing MeCP2

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For those assigned female at birth, they can benefit from BCAAs in the following ways: Staving off early menopause Recent research suggests that metabolic disorders associated with lower circulating BCAAs can result in premature ovarian insufficiency (POI), which can instigate early menopause in some people.8 Women trying to conceive after 40 years of age may consider BCAAs as part of their fertility regimen after consulting a physician

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doi: 10.1016/s0015-0282(16)41541-4