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Even with a single point mutation, correcting enzyme dysfunction is inherently challenging

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Topical formulations are the least expensive choice, while oral preparations are priced in a middle ground between topical and injection therapies

A recent study documented an inverse correlation between the expression of SLC7A11 , the gene encoding xCT subunit, and tumor suppressor p53 in glioblastoma tissues, and also provided strong evidence that p53 binds to SLC7A11 and suppresses its expression [56]

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