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Safety Not recommended for use during pregnancy, lactation or for young children (4,9,22)

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However, a review paper discussing six clinical trials reported that N-acetyl Cysteine is superior to placebo, although with a mild effect, but a large interval of confidence (Nery et al

For example, a patient with a history consistent with IgE-mediated reaction to the antimicrobial sulfonamide trimethoprim-sulfamethoxazole can receive celecoxib, chlorthiazide, furosemide or other nonantimicrobial sulfonamides, as indicated

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