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4 GH counteracts the overall effects of insulin on glucose and lipid metabolism

Introduction Skin envelops the entire surface of human body and is daily exposed to environmental insults such as pathogens, injuries and ultraviolet (UV) radiation

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This observation has been reported in earlier studies in obese and hyperinsulinemic subjects, and in patients with Cushings syndrome, in whom hepatic sensitivity to GH is increased when compared to lean subjects (95, 103)
