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GPX3 can suppress the expression of HIF-1 by regulating ROS, affecting tumor cell energy metabolism, and inhibiting the growth of melanoma cells (51)

pylori infection induces GC cells to express L-plastin via CagA-activated mitogen-activated protein kinase 1 (ERK) signaling pathway to mediate SP1 binding to L-plastin promoter, which promotes proliferation and migration [44]

And do the people using them even care
