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A Novel Three-in-One copper-based metal-organic framework nanozyme eradicates colorectal cancer and overcomes chemoresistance for tumor therapy
Manipulating ferritin levels through ferritinophagy can influence the iron abundance and the susceptibility to ferroptosis ( via various multivesicular bodies and exosomes carrying ferroportin or prominin2-mediated ferritin, can also affect the cellular sensitivity to ferroptosis, as they deplete the cellular iron and accelerate the lipid peroxidation ( Figure 1 )
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10.1021/cr200085w
The victims developed a protracted lethal illness with a disease pattern similar to that of alimentary toxic aleukia (ATA)
