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The primary antidepressant mechanism involves promoting serotonin accumulation in the cerebral cortex

Annals of Surgical Oncology 2011;18 Suppl 3:S1968 (author reply S199)

This is in line with the observations that conditions such as fatigue, headaches, low body temperature, anxiety, panic attacks, PMS, hair loss, depression, low motivation, IBS, insomnia, decreased memory and concentration are all common symptoms in hypothyroidism

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