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Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)

All medications come from licensed 503A compounding pharmacies

10.1016/B978-0-12-381510-1.00007-7 146

Deficiency is more common in men and women who are 50+, as well as vegans who are struggling to get enough of the vitamin through their diet

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