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( C ) Pathway wise gene expression variation between essential and non-essential enzymes: For each metabolic pathway, a set of essential and non-essential enzymes were identified using in silico enzyme knockout experiments and gene expression variation between essential and non-essential enzymes was calculated using the public data obtained from microarray gene expression experiments

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Biochem J 360:116 Shu DF, Wang LY, Duan M, Deng YS, Meng QW (2011) Antisense-mediated depletion of tomato chloroplast glutathione reductase enhances susceptibility to chilling stress