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Historic and current treatments for PD Evolution of care: pharmacological interventions to neuromodulation As far back as the 1940s, the advent of the stereotactic head frame allowed the targeting of subcortical structures with great precision

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In this work, a ginsenoside Rg3 (Rg3)-functionalized biomimetic nanoplatform is fabricated by encapsulating arsenic trioxide (ATO) and chlorin e6 (Ce6) into exosomes, denoted as Rg3-Exo/ATO@Ce6, to ameliorate photoimmunotherapy via reprogramming the tumor microenvironment (TME)