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Doctors adjust the dose based on how the patient responds

The BNF updated their website but the information about frequency remains the same Hydroxocobalamin

Results should be interpreted in clinical context, and patients should receive clear communication about findings and any necessary follow-up investigations or specialist referrals

Methylcobalamin helps regenerate damaged nerves and maintain the myelin sheath, while Pyridoxine and Nicotinamide support neurotransmitter function and cellular repair

NHS loading is 1mg hydroxocobalamin every two days for two weeks, then maintenance every two to three months for life when the cause is non-dietary