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doi:10.2147/ccid.s217956 2

Add to that the lack of a gold-standard test for deficiency, and you can see why its an easy issue to miss

Expression of the angiogenic factors vascular endothelial cell growth factor

However, such an approach is likely beneficial for patients receiving high doses of metformin over an extended period
A microdose is any weekly dose below the 2.5 mg label starter, usually 0.5-2 mg weekly
