glutathione wiki fr File:Glutathion.svg Glutathione-Mediated Conjugation of Anticancer Drugs

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In recent years, there has been rapid development in hydrogel technology for tissue engineering

For example, resistance to several antimetabolite drugs can result from impaired drug uptake into cells, overproduction or reduced affinity of the drug target, upregulation of alternative metabolic pathways, impaired activation or increased inactivation of the antimetabolite, as well as increased drug (or metabolite) efflux

38,390,391 L-tryptophan is also a precursor to melatonin and vitamin B3, as well as several other metabolites