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Furthermore, researchers discovered that osmundacetone (OSC), a bioactive phenolic compound derived from Phellinus igniarius, exhibited regulatory effects on the immune microenvironment, as confirmed by downregulation of GLUD1 expression upon OSC treatment [211]

Xie P, Parsons SH, Speckhard DC, Bosron WF, Hurley TD

Moringin was able to initiate intrinsic apoptosis pathway by upregulating caspases2 and 9, increasing the amount of intracellular reactive oxygen species and decreasing the activity of the BIRC5 (baculoviral inhibitor of apoptosis protein (IAP) repeat containing 5) prosurvival gene (Antonini et al., 2018)