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This coordinated developmental trajectory indicates that the downregulation of CCK-positive excitatory neurons is not accompanied by a compensatory increase in CCK-positive inhibitory interneurons and therefore cannot be attributed to an excitatory-to-inhibitory expression shift
No animal showed clinical signs of the disease during the experiment
Cell signaling in interstitial cystitis/painful bladder syndrome
The PD therapeutic strategy of each clinical trial shows 29, 5, 1, 5, 5, and 2 clinical trials use small molecules, monoclonal antibodies, plasma therapy, cell therapies, gene therapies, and herbal extracts, respectively
62 Inhibition of TRPV4, a calcium-permeable cation channel, suppresses the polarization of M1 macrophages in synovium via the ROS/NLRP3 pathway, thereby delaying OA progression
