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Vitamin B12 deficiency can occur due to many reasons, mainly improper diet or you have a condition where your body can't absorb as much.

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GSH depletion and concomitant increase in O&NS and mitochondrial dysfunctions play a role in the pathophysiology of diverse neuroimmune disorders, including depression, myalgic encephalomyelitis/chronic fatigue syndrome and Parkinsons disease, suggesting that depleted GSH is an integral part of these diseases

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