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Relying on one without the other introduces uncertainty
Specifically, HER2 + breast cancer patients having received anti-HER2 targeted therapies exhibited a high risk of developing lung metastasis [44, 45], and TN breast cancers have high propensities to metastasize to the lung [42, 46]

The Connectivity Map (CMap) is a database maintained by the Broad Institute that catalogs how small molecules affect gene expression across the human genome

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