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These findings add to a growing literature examining Semax in models of depression and anxiety, and complement earlier preclinical data demonstrating Semax's attenuation of stress-induced cognitive and behavioural deficits in rodent models of chronic stress

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pharmacological inhibition of NNMT has therefore become a major focus in laboratory research on adipose-tissue energy balance, methyl-donor recycling, and metabolic resilience

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However, its specificity for the fibrotic pathology of frozen shoulder makes it an important peptide to watch in this space
