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It was found that probiotics VSL#3 treatment could upregulate the expression of microRNA-146a (miR-146a) and block the BTG2/Bax (B-cell translocation gene 2/Bcl-2-associated X protein) axis in POCD mice, thus inhibiting neuronal apoptosis and reducing oxidative stress (Mao et al., 2021)

Cartilage and joint repair models: Intraarticular injection of AOD9604 in a collagenase induced rabbit osteoarthritis model showed improved cartilage architecture and regeneration

doi: 10.1016/j.jddst.2021.103091 [DOI] [Google Scholar] 40.Warnken ZN, Smyth HD, Watts AB, Weitman S, Kuhn JG, Williams RO