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ROS, including O 2 , H 2 O 2 , and OH, serve as critical signaling molecules that bolster immune responses through their role in both innate and adaptive immunity

There's no published research showing any sort of negative interactions between the two

Significantly, macrophages play a crucial role in the pathogenesis of the inflammatory and autoimmune disorders seen in HUA and its subsequent complications (33, 34) ( Figure 2 )

( Epub 2021 Jul 8 PMID: 34235974 ) Morand E, Pike JT, Merrill R (2022) Efficacy and safety of deucravacitinib, an oral, selective, allosteric TYK2 inhibitor, in patients with active systemic lupus erythematosus: a phase 2, randomized, double-blind, placebo controlled study

Updated January 15, 2025