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In a review of studies, researchers found that while vitamin B12 supplementation did not improve depressive symptoms, low vitamin B12 levels were linked to an increased risk of developing depression

Likewise, symptoms of vitamin B12 can also resemble anemia or fatigue, causing some people to think that they are simply tired

Other causes are conditions affecting the stomach or small intestine, such as Crohns disease, operations such as gastrostomies (which involve removal of part of the stomach), and certain medications

My legs would constantly ache also which was horrible, along with restless legs which I used to think was a myth

The American journal of clinical nutrition 2024
