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The clinical significance of the VMAT transporters is evidenced by the fact that variants in VMAT1 have been found to be associated with susceptibility for schizophrenia and bipolar depression

King R, Tuthill C

Cell 33 GaoM.YiJ.ZhuJ.MinikesA

This causes more glutamate to remain in the synapse.[ref] Animal studies show that aspartame causes anxiety-like behavior and learning and memory deficits

GRADE-assessed systematic review and meta-analysis of clinical trials
