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One hundred fifty-three of 1027 metabolites assayed were significantly different based on disease status and 474 metabolites were nominally significant (Supplementary Table S1)

In addition to shuttling fatty acids into the mitochondria for energy production, carnitine also shuttles potentially toxic compounds out of the mitochondria, which protect the availability of free Coenzyme A (CoA)

Both the GAD1 and GAD2 genes are expressed in the brain and GAD2 expression also occurs in the pancreas

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