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Description
They document relevant pre-existing toxicological data, justification for dose selection, and all procedural details related to chemical administration

Shin Y, Choi SH, Kim E, Bylykbashi E, Kim JA, Chung S, Kim DY, Kamm RD, Tanzi RE

The Cochrane review also underscored the need to include a measurement of the quality of life as an outcome, and patient preference at the time of prescribing treatment

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