metastatic melanotic peripheral nerve sheath A para-aortic malignant tumor mimicking a gastrointestinal stromal tumor: a rare case report and review of literature | BMC Surgery Rare malignant melanotic nerve sheath

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Oncogenic alterations [10, 18,19,20,21] reshape lipid metabolic pathways at the transcriptional and posttranscriptional levels, while microenvironmental cues, such as growth factors, nutrient availability, and metabolic stresses, such as hypoxia further sculpt this metabolic network

This increase in ROS generation by the respiratory chain exacerbates oxidative stress, further amplifying the inflammatory process

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