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Description
This structural information is invaluable for the rational design of new therapeutic agents targeting the GHRHR
For example, in obesity, increased leptin levels bind to leptin receptors on astrocytes, activating the JAK/STAT signaling pathway
Halkos, S.M
[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Klubo-Gwiezdzinska J., Wartofsky L
Preprint at bioRxiv (2025)
