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The peptide also modulates MMP activity and expression, creating a balanced proteolytic environment that allows removal of damaged, fragmented collagen while protecting newly synthesized fibers

Apoptosis of melanocytes is involved in the pathogenesis of Vitiligo

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Photographs of affected area if visible swelling or deformity
A review in JAAOS Global Research & Reviews mapped these peptides across PI3K/Akt, mTOR, TGF-, and AMPK signaling pathways, suggesting their role in musculoskeletal healing (Rahman, Lee & Seeds, JAAOS Global R&R , 2026)