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USA 110 , E170 (2013)

Evidence derived from human observational studies, autopsy findings, and experimental models suggests that sustained androgen receptor overstimulation may induce structural, functional, and metabolic alterations that compromise cardiovascular homeostasis (68, 69)

To arrive at suitable cutoff values, the sensitivity associated with various cutoffs used in MetDP was explored (see Additional file 1: Figures S1 and S2)

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One vial, four weeks, done