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6,335,352,355,357 To further substantiate the role of LPAR1/2 in pulmonary fibrosis, pharmacological inhibition of LPAR1 (e.g., Ki16425, AM966, and BMS-986020) attenuated fibrosis and inflammatory cytokine production in mice, and BMS-986020 demonstrated clinical benefit in IPF patients in phase II trials

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The redox requirements of proliferating mammalian cells

Since mitochondria are thought to be the main source of reactive oxygen species (ROS), dysfunctions in these organelles lead to redox alterations in disease [4]

The FDA Adverse Event Reporting System now shows a reporting odds ratio of 2.46 for alopecia with semaglutide, meaning hair loss reports are nearly two and a half times higher than expected