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For example, Solt et al

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Due to cardiomyocytes requiring massive energy demands, they are rich in mitochondria standing out from the rest of the cell type [15, 16], which makes them very sensitive to oxidative stress damage

These studies have relied on conventional methods for measuring these metabolites and there is lack of agreement among different reports about the absolute values and the form of glutathione being effluxed 2,21,22,23